N-BETA-MALEIMIDOPROPIONIC ACID
N-maleoyl-beta-alanine
CAS: 7423-55-4
Molecular Formula: C7H7NO4
N-BETA-MALEIMIDOPROPIONIC ACID - Names and Identifiers
| Name | N-maleoyl-beta-alanine |
| Synonyms | MPA-OH AKOS BC-0729 RARECHEM AL CD 0912 N-maleoyl-beta-alanine N-MALEOYL-BETA-ALANINE 3-MALEIMIDOPROPIONIC ACID 3-Maleimidopropionic acid N-(2-CARBOXYETHYL)MALEIMIDE N-BETA-MALEIMIDOPROPIONIC ACID 3-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid |
| CAS | 7423-55-4 |
| EINECS | 616-069-0 |
| InChI | InChI=1/C7H7NO4/c9-5-1-2-6(10)8(5)4-3-7(11)12/h1-2H,3-4H2,(H,11,12) |
| InChIKey | IUTPJBLLJJNPAJ-UHFFFAOYSA-N |
N-BETA-MALEIMIDOPROPIONIC ACID - Physico-chemical Properties
| Molecular Formula | C7H7NO4 |
| Molar Mass | 169.13 |
| Density | 1.473±0.06 g/cm3(Predicted) |
| Melting Point | 103-106 °C (lit.) |
| Boling Point | 382.5±25.0 °C(Predicted) |
| Flash Point | 185.1°C |
| Water Solubility | Soluble in methanol, dimethyl formamide, alcohol and dimethyl sulfoxide. Slightly soluble in water. |
| Solubility | Soluble in water (partly), DMF, methanol, and DMSO. |
| Vapor Presure | 6.53E-07mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| BRN | 1528952 |
| pKa | 4.18±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.565 |
| MDL | MFCD00043030 |
| Use | A sulfhydryl reactive heterobifunctional crosslinking reagent. |
N-BETA-MALEIMIDOPROPIONIC ACID - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29252900 |
N-BETA-MALEIMIDOPROPIONIC ACID - Introduction
3-Maleimidopropionic Acid is a sulfhydryl reactive heterobifunctional crosslinking reagent.
Last Update：2024-04-09 19:55:45
N-BETA-MALEIMIDOPROPIONIC ACID - Reference Information
| Introduction | 3-maleimidyl propionic acid is a carboxylic acid derivative, changing the thiol group to carboxyl group, for the preparation of peptide-protein crosslinks. |
| Application | 3-maleimidyl propionic acid is a carboxylic acid derivative, which can be used as an intermediate in organic synthesis and medicine. |
| biological activity | 3-maleimidopionic acid is a PROTAC linker based on alkyl chain, which can be used in the synthesis of PROTAC. |
Last Update：2024-04-09 19:55:45
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